Spin valve like AF/Fe/Cu/Fe (AF = Fe₅₀Mn₅₀ and Ir₅₀Mn₅₀) multilayer systems have been prepared by molecular beam epitaxy. Thin tracer layers enriched in the ⁵⁷Fe isotope were artificially grown at the AF/Fe and Fe/Cu interfaces and the interfacial atomic diffusion was observed via ⁵⁷Fe conversion electron Mössbauer spectroscopy. The results show that the atomic interdiffusion at all involved interfaces is lower in the IrMn based structures as compared to the FeMn based ones.